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Probiotics: Benefits, Side Effects and How to Choose One

What probiotics are, the health benefits that have real evidence behind them, who should avoid them, and how to choose a supplement or food.

By Editorial Team · Updated · 2 min read

Bowl of creamy fruit yogurt with a spoon
Photo: U.S. Department of Agriculture · CC0

This article is awaiting review by a qualified medical professional.

Quick answer

Probiotics are live microorganisms, usually bacteria or yeast, that can benefit health when taken in adequate amounts. The best-supported benefits are reducing antibiotic-associated diarrhea, shortening some infectious diarrhea, and easing symptoms in some people with irritable bowel syndrome. Effects depend on the specific strain, and they are not suitable for everyone.

Probiotics are live microorganisms that, when taken in adequate amounts, can benefit your health. They are found in some foods and are sold as supplements. The most common types belong to the groups Lactobacillus and Bifidobacterium, and the yeast Saccharomyces boulardii.

Benefits of probiotics

Research shows that probiotics work best for specific problems, and that each strain behaves differently. The benefits with the strongest evidence are:

  • Preventing antibiotic-associated diarrhea: some strains reduce the chance of diarrhea while taking antibiotics
  • Shortening infectious diarrhea: in children, certain probiotics can shorten a bout of acute diarrhea by about a day
  • Easing irritable bowel syndrome (IBS): some people have less bloating, pain and gas, though results are mixed
  • Supporting ulcerative colitis: certain combinations may help maintain remission alongside standard treatment
  • Protecting premature babies: doctors sometimes use specific probiotics in hospital to reduce a serious bowel condition, and this should only be done under medical supervision

Claims that probiotics boost immunity, help weight loss or improve general wellbeing in healthy people are not well proven.

Foods that contain probiotics

  • Yogurt and kefir with "live and active cultures"
  • Sauerkraut and kimchi (unpasteurised)
  • Miso and tempeh
  • Some kombucha and fermented pickles

Foods called prebiotics feed the good bacteria already in your gut. They include oats, bananas, onions, garlic, leeks, asparagus and legumes.

Side effects and risks

Most people have no problems. Mild effects can include gas, bloating and loose stools during the first few days.

Probiotics can occasionally cause serious infections in:

  • People with weakened immune systems, for example during chemotherapy or after a transplant
  • Critically ill patients or those with a central venous catheter
  • Premature infants, unless given by a hospital team
  • People with severe pancreatitis

Supplements are not regulated like medicines in many countries, so the strains and amounts on the label may not match what is inside.

How to choose a probiotic

  1. Match the strain to your goal. Look for the full name, for example genus, species and strain, such as Lactobacillus rhamnosus GG
  2. Check the dose in colony-forming units (CFU) guaranteed until the expiry date
  3. Choose products tested by a third party where possible
  4. Follow storage instructions, as some need refrigeration
  5. Give it a trial period of a few weeks, and stop if it does not help

When to see a doctor

Speak to a doctor before starting probiotics if you are immunocompromised, seriously ill or pregnant, or if you are giving them to a baby. See a doctor if you have persistent diarrhea, blood in your stool, unexplained weight loss or severe abdominal pain, rather than treating it yourself with supplements.

Frequently asked questions

What are the main benefits of probiotics?

The best evidence is for preventing antibiotic-associated diarrhea, shortening acute infectious diarrhea (especially in children) and easing symptoms in some people with irritable bowel syndrome. Benefits are strain-specific, and there is little proof that healthy people gain much from taking them.

Are probiotics safe to take every day?

For most healthy people they are safe, and side effects are usually mild gas or bloating. They can cause serious infections in people with weakened immune systems, people who are critically ill, and premature babies, so ask a doctor first if that applies to you.

Are yogurt and fermented foods as good as probiotic supplements?

Yogurt with live cultures, kefir, sauerkraut and kimchi can add beneficial microbes to your diet, but the strains and amounts are not standardised. Supplements contain defined strains and doses, but quality varies between products.

When is the best time to take a probiotic?

Follow the product label, because it depends on the strain and formulation. If you are taking antibiotics, take the probiotic a couple of hours apart from the antibiotic dose.

Sources

  1. NIH National Center for Complementary and Integrative Health: Probiotics, usefulness and safety
  2. NIH Office of Dietary Supplements: Probiotics fact sheet

This article is for educational purposes only and does not replace advice from a doctor or other qualified health professional. See our medical disclaimer.